The study of the impact of assistive technologies to enhance and facilitate independent navigation throughout the city in people who are blind has been highlighted by the literature in the last decade. In this work we present some issues concerning mobile devices for cognition of people who are blind as a result of research studies involving the design, development, evaluation and use of three mobile applications (mBN, AudioTransantiago, AmbientGPS) for outdoor assistance navigation in the city to address orientation and mobility issues. The studies involved usability and cognitive evaluation processes with end users that raised some issues that are presented and discussed in this paper. The users through the interaction with mobile applications to assist blind learners in their everyday orientation and mobility tasks achieved independence and autonomy to their navigation in real unknown context throughout the city.